Phospho-Akt2 (S474) Polyclonal Antibody, 50ul Antibodies Mutations in this gene have

Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP)

This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria

Polymorphism within this gene is associated with variable ability to metabolize mephenytoin

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints

In experiments with non-human species

Phospho-Akt2 (S474) Polyclonal Antibody, 50ul Antibodies Mutations in this gene haveAKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine threonine kinases containing SH2 like (Src homology 2 like) domains. AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT serine threonine kinase 2 is a general protein kinase capable of