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Understanding the evidence, safety considerations, and lack of proven synergistic benefit is essential for informed clinical decision-making when patients consider combining these treatments

K-means clustering was performed on the genera relative abundance data using the R script in the Supplementary Materials Scripts .zip file (KMScript), and clusters were plotted

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2020) confirmed that B12 levels at or above 1,000 ng/L were associated with solid cancers: OR 1.96 for cancers without metastases and OR 4.21 for cancers with metastases, after adjusting for all other causes of elevated B12

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