Rat Annexin A1, ANXA1 ELISA Kit, 96T Proteases The protein encoded by PFKFB2

The protein encoded by PFKFB2 (6-phosphofructo-2-kinase/fructose-2

Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed: 18511561)

Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin (PubMed: 11483589)

The protein encoded by this gene belongs to the SMAD

RCBTB1 maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies

Rat Annexin A1, ANXA1 ELISA Kit, 96T Proteases The protein encoded by PFKFB2Plays important roles in the innate immune response as effector of glucocorticoid mediated responses and regulator of the inflammatory process. Has anti inflammatory activity. Plays a role in glucocorticoid mediated down regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl Peptide receptors and downstream signaling