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Glucose / IGF-1: Higher GH output can affect insulin sensitivity

A head-to-head trial (SURMOUNT-5) reported greater weight loss with tirzepatide than semaglutide in adults with obesity

10.1002/(sici)1097-0215(19981209)78:6& 3.0.co;2-j Int J Cancer

Generics to dramatically cut cost: experts Novo Nordisk the company behind blockbuster diabetes and weight-loss drugs Ozempic and Wegovy had for years held a patent on semaglutide, the active ingredient in those drugs that triggers the release of insulin and is used to treat diabetes and to aid weight loss