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ERK5 is a known weak client of Hsp90, and prolonged occupancy of the N-terminal ATP-binding pocket by potent inhibitors such as ganetespib or by HLX itself destabilizes a subset of Hsp90 clients, including ERK5 [48,49,50]

It is widely studied for its potential neuroprotective, neurotrophic, and cognitive-enhancing properties

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Particularly relevant for implant patients over 45

Doctor was upfront that it is off-label and individual