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Retatrutide adds the "output" side

Another notable finding is that compared to other GLP-1RAs, semaglutide or tirzepatide is associated with increased risks of optic neuropathy and other optic nerve disorders

Important Update: Compounded Tirzepatide Phasing Out

Adding it to a metabolic peptide sounds contradictory, and that apparent contradiction is exactly why the triple agonists are scientifically interesting