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PI 3-kinase p85 Beta Polyclonal Antibody, 50ul[BT-AP07147] Cell Culture Dishes This gene encodes an enzyme

SKU: 91360501798

4.0
SEK162.00 SEK192.00

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PI 3-kinase p85 Beta Polyclonal Antibody, 50ul[BT-AP07147] Cell Culture Dishes This gene encodes an enzymePhosphatidylinositol 3 kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. Phosphoinositide 3 kinase regulatory subunit 2 encoded by PIK3R2 is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non protein coding, have been found

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Description

This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation of proteins

Two alternative transcripts have been found| a constitutively expressed transcript and a cell cycle-regulated transcript| that is expressed predominantly during G2/M phase

Catalytic activity:Release of an N-terminal dipeptide| Xaa-Yaa-|-Zaa-| except when Xaa is Arg or Lys| or Yaa or Zaa is Pro

Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer

May play a functional role in the immune system

PI 3-kinase p85 Beta Polyclonal Antibody, 50ul[BT-AP07147] Cell Culture Dishes This gene encodes an enzymePhosphatidylinositol 3 kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. Phosphoinositide 3 kinase regulatory subunit 2 encoded by PIK3R2 is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non protein coding, have been found

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