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SIGIR Polyclonal Antibody, 20ul Filtration Activated by phosphorylation at Thr-838|

SKU: 72491937609

4.6
PLN111.00 PLN137.00

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SIGIR Polyclonal Antibody, 20ul Filtration Activated by phosphorylation at Thr-838|Acts as a negative regulator of the Toll like and IL 1R receptor signaling pathways. Attenuates the recruitment of receptor proximal signaling components to the TLR4 receptor, probably through an TIR TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.,Belongs to the interleukin 1 receptor family.,Contains 1 Ig like C2 type (immunoglobulin like) domain.,Contains 1 TIR

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Description

Activated by phosphorylation at Thr-838| inhibited by phosphorylation at Ser-966 and Ser-1033

which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides

The use by some variants of an alternate promoter in an up

The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta

This protein also interacts with transcription factor AP2 (TFAP2)

SIGIR Polyclonal Antibody, 20ul Filtration Activated by phosphorylation at Thr-838|Acts as a negative regulator of the Toll like and IL 1R receptor signaling pathways. Attenuates the recruitment of receptor proximal signaling components to the TLR4 receptor, probably through an TIR TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.,Belongs to the interleukin 1 receptor family.,Contains 1 Ig like C2 type (immunoglobulin like) domain.,Contains 1 TIR

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