SIGIR Polyclonal Antibody, 20ul Filtration Activated by phosphorylation at Thr-838|
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SIGIR Polyclonal Antibody, 20ul Filtration Activated by phosphorylation at Thr-838|Acts as a negative regulator of the Toll like and IL 1R receptor signaling pathways. Attenuates the recruitment of receptor proximal signaling components to the TLR4 receptor, probably through an TIR TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.,Belongs to the interleukin 1 receptor family.,Contains 1 Ig like C2 type (immunoglobulin like) domain.,Contains 1 TIR
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