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INDICATIONS SPRYCEL (dasatinib) is indicated for the treatment of adult patients with: SPRYCEL is indicated for the treatment of pediatric patients 1 year of age and older with: Tablet dosing for pediatric patients 1 Tablet dosing is not recommended for patients weighing less than 10 kg

Multiple systematic reviews and meta-analyses of randomized controlled trials now report that, in women with PCOS, GLP-1 receptor agonists produce significant reductions in body weight, BMI, and waist circumference, together with improvements in insulin resistance measured as fasting insulin and HOMA-IR, modest reductions in total testosterone, and increases in SHBG

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For obesity, the dose went down from 50 mg with the original formulation to 25 mg with the new formulation