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Endocrinology 127 , 32343236 (1990)

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Nettle Extract Rich in antioxidant compounds, Nettle supports oxidative balance and contributes to joint comfort and tissue health

In animal and cell studies it is associated with upregulation of repair-related growth-factor and angiogenic signalling (for example VEGF-linked pathways), collagen and extracellular-matrix (ECM) remodelling, and modulation of inflammation, which underlies research interest in connective-tissue and gut-lining recovery

I know Ive seen research showing it raises it but im skeptical as to whether it raises it high enough to make a difference