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10.1016/s0090-9556(24)14957-4 16 Gonzalez-SalesM.HolfordN.BonnefoisG.DesrochersJ

L., Dixon, K

The Purpose of the Work Acute pancreatitis after ERCP intervention is the most frequent complication and its etiology is not clearly understood

To verify the importance of pocket size for ligand recognition of ShHTLs, a double mutation T190F/C194F and a triple mutation L124F/T190F/C194F of ShHTL7 were generated to introduce large side-chain amino acids to reduce the pocket size by partially mimicking ShHTL3