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The secondary outcomes comprising cardiometabolic risk factors (including high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), body mass index (BMI), insulin sensitivity index adjusted for BMI (ISI), systolic blood pressure (SBP), diastolic blood pressure (DBP)) [33] and multiple-organ complications (liver diseases: metabolic dysfunction-associated steatohepatitis, liver fibrosis, fibrosis in MASLD, liver cirrhosis, hepatocellular carcinoma (HCC), hepatic failure