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DERL1 Polyclonal Antibody, 20ul Cell Function Analysis The encoded protein is found

SKU: 22462699085

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DERL1 Polyclonal Antibody, 20ul Cell Function Analysis The encoded protein is foundThe protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance

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Description

The encoded protein is found to be associated with centromeres of mitotic HeLa cells| which suggests that this protein is a functional homolog of yeast Nuf2

With its conical bottom design

neural-specific gene which plays an unspecified role in early embryogenesis

The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA

RBSN encodes a protein that belongs to the FYVE zinc finger family of proteins

DERL1 Polyclonal Antibody, 20ul Cell Function Analysis The encoded protein is foundThe protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance

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